安吉拉•约翰逊 View All Faculty
教师图片.

Disciplines/Field of Instruction

  • 生物学

Degrees Received

  • Ph.D., 2008, Pathology, Case Western Reserve University, Cleveland, OH
  • B.S., 2001, 生物学, 新濠天地app大学, Beaver Falls, PA

课程

  • BIO 112 - Cell 生物学
  • BIO 120 - Fundamental Human Anatomy and Physiology I (labs)
  • BIO 121 - Fundamental Human Anatomy and Physiology II
  • BIO 225 - Human Anatomy and Physiology I
  • BIO 315 - Immunology

Presentations / Publications

  • Alexandria David, Megan MacLeod, 安吉拉·C. Johnson, Philippa Marrack and 三个一组N. Jørgensen. 2014. Intrinsic autoimmune capacities of hematopoietic cells from female New Zealand hybrid mice. Genes and Immunity. 15 (3): 153-161. (PMID: 24477163)
  • 安吉拉·C. Johnson, Ayesha Khan, Elena Gonzalez, Laura M. Davison, Xiaoxia Li, and 三个一组N. 约根森. Lack of IRAK4 leads to systemic abscess formation and early lethality but does not impair autoimmunity in Act1-deficient mice. 2014. Annual Meeting of the Federation of Clinical Immunology Societies (FOCUS), Chicago, Illinois.
  • 安吉拉·C. Johnson, Laura Davison, Natalia V. Giltiay, Chairut Vareechon, Xiaoxia Li and 三个一组N. Jørgensen. 2012. Lack of T cells in Act1-deficient mice results in elevated IgM-specific autoantibodies but reduced lupus-like disease. European Journal of Immunology. 42 (7): 1695-1705. (PMID: 22585710)
  • 安吉拉·C. Johnson, Xiaoxia Li, and 三个一组N 约根森. T cells, but not TLRs, control Act1-driven autoimmunity. 2010. Annual Meeting of the American Association of Immunologists, Baltimore, Maryland.
  • 三个一组N. Jørgensen, Natalia V. Giltiay, 安吉拉•约翰逊, Xiaoxia Li. 2009. “Chapter 4: The role of Act1 in the control of autoimmunity” in The Epigenetics of Autoimmune Disease. Editor: Moncef Zouali, Publisher: John Wiley & 儿子公司. ISBN: 9780470758618.
  • 安吉拉·C. Johnson, Xiaoxia Li, and Eric Pearlman. 2008. MyD88 functions as a negative regulator of TLR3/TRIF-induced corneal inflammation by inhibiting activation of c-Jun N-terminal kinase. Journal of Biological Chemistry. 283 (7): 3988-3996. (PMID: 18057004).
  • Eric Pearlman, 安吉拉·C. Johnson, Gautam Adhikary, Yan Sun, Holly R. Chinnery, Todd Fox, Mark Kester, and Paul G. McMenamin 2008. Toll-like Receptors at the ocular surface. The Ocular Surface. 6 (3): 108-116. (PMID: 18781257)
  • 安吉拉·C. Johnson, Megan K. L. Macleod, Alexandria David, Philippa Marrack, and 三个一组N. 约根森. Gender-Related Differences in the Bone Marrow of Lupus-Prone Mice. 2008. Lupus Autoimmunity: Mechanisms and Immune Regulation, Biosymposia, Inc., La Jolla, California.
  • Natalia Giltiay, Youcun Qian, 安吉拉·C. 约翰逊,三个一组N. 约根森, and Xiaoxia Li. Act1-Deficient Mice as a Model of SLE: Insights into the Cellular and Molecular Mechanisms of the Disease Development. 2008. Lupus Autoimmunity: Mechanisms and Immune Regulation, Biosymposia, Inc., La Jolla, California.
  • 安吉拉·C. Johnson, Yan Sun, and Eric Pearlman. MyD88 negatively regulates TLR3/TRIF-induced corneal inflammation through c-Jun N-terminal kinase (JNK). 2007. Society for Leukocyte 生物学, Annual Meeting of the Society for Leukocyte 生物学, 波士顿, 麻萨诸塞州. (Selected oral presentation, Presidential Student Award)
  • 安吉拉·C. 弗雷德·约翰逊. Heinzel, Eugenia Diaconu, Yan Sun, Amy G. Hise, Douglas Golenbock, Jonathan H. Lass, and Eric Pearlman. 2005. Activation of Toll-Like Receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation. Investigative Ophthalmology and Visual Sciences. 46 (2): 589-595. (PMID: 15671286)
  • 安吉拉·C. Johnson and Eric Pearlman. 2005. Toll-like Receptors in the cornea. The Ocular Surface. 3 (4): S187-S189. (PMID: 17216116)

当前的项目

  • Understanding Innate Immune mechanisms of the body, specifically macrophages, Toll-like Receptors, 和细胞因子.

从属关系

  • Center for Bioethics and Human Dignity
  • American Association of Immunologists

委员会

  • Pre-Med Committee
  • Faculty Policy and Development Committee
  • 生物学 Department Search Committee
  • Department Chair
  • Campus 领导 Group

杂项

  • I enjoy reading, cooking, and spending time with my husband and three children.
  • Our family attends Pathway Church.

Academic Distinctives

Dr. Johnson has worked with several students, 2021年, she worked with a student who was a Noyce scholar, to grow a mouse macrophage cell line (J774), treated the cells with Toll-like Receptor (TLR) ligands, and assess cytokine production via ELISA.

Dr. Johnson is affiliated with the Center for Bioethics and Human Dignity and the American Association of Immunologists.